• Frontiers | Improved Alignment of PEDOT:PSS Induced by …

    Dimethylsulfone (DMSO2), a small organic molecule, was observed to induce the alignment of poly(3,4-ethylenedioxythiophene): poly(4-styrenesulfonate) (PEDOT:PSS) via in-situ crystallization in PEDOT:PSS mixture, which was …Energy barriers to anion transport in polyelectrolyte ...2020-5-15 · Membrane thickness increased significantly with the addition of bilayers to the PEMs while pore size and surface zeta potential were comparatively unaffected ().The similarity in pore size was particularly important for measurements of energy barriers to ion transport through the membranes, given the reported effect of steric hindrance on ion dehydration (i.e., greater need …

  • Molecular dynamics simulations of ion transport through ...

    2010-4-28 · Extensive molecular dynamics simulations of the flow of aqueous NaCl and NaI solutions through carbon nanotubes are presented, evidencing the dependence of diverse transport features on the solute specificity, the nanotube geometry, and the various atomic models employed, including polarizability. The simulated properties are in agreement with published …Superlattice of Single Atom Magnets on Graphene | Nano …Regular arrays of single atoms with stable magnetization represent the ultimate limit of ultrahigh density storage media. Here we report a self-assembled superlattice of individual and noninteracting Dy atoms on graphene grown on Ir(111), with magnetic hysteresis up to 5.6 T and spin lifetime of 1000 s at 2.5 K. The observed magnetic stability is a consequence of the …

  • Frontiers in the treatment of glioblastoma: Past, present ...

    2021-4-1 · 1. Introduction. Glioblastoma (GBM) is one of the most malignant types of tumours affecting the brain, accounting for greater than 60% of all brain tumours in adults [1,2].GBM also affects paediatric populations accounting for about 3% of all brain tumours [].Patients with GBM typically present with confusion, memory deficit, focal or progressive neurologic issues, …Energy barriers to anion transport in polyelectrolyte ...2020-5-15 · Membrane thickness increased significantly with the addition of bilayers to the PEMs while pore size and surface zeta potential were comparatively unaffected ().The similarity in pore size was particularly important for measurements of energy barriers to ion transport through the membranes, given the reported effect of steric hindrance on ion dehydration (i.e., greater need …

  • Carbon Dots: An Innovative Tool for Drug Delivery in Brain ...

    The pharmacological treatment of tumors of the central nervous system poses major challenges due to the presence of physical obstacles, i.e., the blood-brain barrier, impeding the delivery of anticancer drugs to the tumor site. Hence, the development ...Molecular dynamics simulations of ion transport through ...2010-4-28 · Extensive molecular dynamics simulations of the flow of aqueous NaCl and NaI solutions through carbon nanotubes are presented, evidencing the dependence of diverse transport features on the solute specificity, the nanotube geometry, and the various atomic models employed, including polarizability. The simulated properties are in agreement with published …

  • Molecular dynamics simulations of ion transport through ...

    2010-4-28 · Extensive molecular dynamics simulations of the flow of aqueous NaCl and NaI solutions through carbon nanotubes are presented, evidencing the dependence of diverse transport features on the solute specificity, the nanotube geometry, and the various atomic models employed, including polarizability. The simulated properties are in agreement with published …Albumin-based drug delivery: harnessing nature to cure …2015-11-13 · Biological properties of albumin. Albumin is the most abundant plasma protein in human blood (35–50 g/L human serum) with a molecular weight of 66.5 kDa [] is synthesised in the liver hepatocytes with ~ 10–15 g of albumin produced and released into the vascular space daily [10, 12].Circulation in the blood proceeds for an extended period of ~ 19 days [10, 13, 14].

  • Frontiers | Improved Alignment of PEDOT:PSS Induced by …

    2015-9-18 · To generate effective antimicrobial peptides (AMPs) with good antimicrobial activities and cell selectivity, many synthetic strategies have been implemented to facilitate the development of AMPs. However, these synthetic strategies represent only a small proportion of the methods used for the development of AMPs and are not optimal with the requirements …Albumin-based drug delivery: harnessing nature to cure ...2016-2-27 · The effectiveness of a drug is dependent on accumulation at the site of action at therapeutic levels, however, challenges such as rapid renal clearance, degradation or non-specific accumulation requires drug delivery enabling technologies. Albumin is a natural transport protein with multiple ligand binding sites, cellular receptor engagement, and a long circulatory half-life …

  • Albumin-based drug delivery: harnessing nature to cure …

    2015-11-13 · Biological properties of albumin. Albumin is the most abundant plasma protein in human blood (35–50 g/L human serum) with a molecular weight of 66.5 kDa [] is synthesised in the liver hepatocytes with ~ 10–15 g of albumin produced and released into the vascular space daily [10, 12].Circulation in the blood proceeds for an extended period of ~ 19 days [10, 13, 14] parative study of response of four crop species …2021-7-1 · After exposure, leaf fresh biomass (Fig. 1B) was also significantly impacted with an increase of 55% for rapeseed and 71% for cucumber (p-value = 0.021 and 0.041, respectively) but remained unchanged for the other two species with a trend to decrease for maize.Maize had the highest leaf fresh biomass (1225 mg on average, 5.6 times more than rapeseed, 6 times …

  • Gas sensors based on mass-sensitive transducers. Part 2 ...

    2020-7-31 · As discussed in the introduction to the first part of the review [], the development of gas sensors (GS) was driven by the increasing need for the detection of environmental, industrial and domestic chemical hazards.As a result of sustained investigations performed in the 1980s and 1990s, a greater understanding of gas sensing mechanisms based on mass-sensitive …Nanomechanical characterization of pressurized elastic ...2020-1-1 · In this work, we focus on two different types of vesicles of zero spontaneous curvature. The vesicle of the first type is assumed to have a fixed total surface area A (= 4 π R 2) and its bending deformation obeys the Canham–Helfrich model .Therefore, the total system energy at the indentation depth Δ h is described by the Helfrich functional as,, E tot = 2 κ ∫ M 1 2 d A 1 + 2 …

  • New Inorganic–Organic Hybrid Materials for HPLC …

    Nanostructured, mesoporous inorganic–organic hybrid xerogels were reproducibly synthesized by a sol–gel procedure. For the introduction of long alkyl chains into inorganic polymers, trifunctional n ‐alkyltrialkoxysilanes of the type CH 3 (CH 2) n Si(OR) 3 (n = 7, 11, 17; R = CH 3, C 2 H 5) were co‐condensed with Si(OEt) 4 (TEOS). The synthetic pathway involves the employment of n ...Always on the bright side: the climbing mechanism of ...2010-12-8 · Galium aparine is a herbaceous climbing plant that attaches to host plants mainly via its leaves, which are covered by hooked trichomes. Although such hooks are found on both leaf surfaces, the leaves of G. aparine are mainly positioned upon the leaves of supporting plants and rarely beneath. In order to understand the mechanism underlying this observation, we have …

  • Rational design of mirror-like peptides with alanine ...

    2015-9-18 · Amino acids sequence distribution on helical wheel projections. By default the output of presented the amino acid residues as circles.Hydrophobic residues were coded X and blue background.Cationic residues were coded Y and red background.Dotted lines represented symmetrical axis on helical wheels.Left 13-amino acid in length was a perfectly amphipathic α …Albumin-based drug delivery: harnessing nature to cure ...2016-2-27 · The effectiveness of a drug is dependent on accumulation at the site of action at therapeutic levels, however, challenges such as rapid renal clearance, degradation or non-specific accumulation requires drug delivery enabling technologies. Albumin is a natural transport protein with multiple ligand binding sites, cellular receptor engagement, and a long circulatory half-life …

  • KIT

    S. Reißer, E. Strandberg, T. Steinbrecher, M. Elstner, A.S. Ulrich. Best of two worlds? How MD simulations of amphiphilic helical peptides in membranes can complement data from oriented solid-state NMR. J. Chem. Theory Comput. 14, 6002-6014 (2018)Design and Application of Near-Infrared Nanomaterial ...1. Introduction. Currently, cancer treatment mainly relies on chemotherapeutic drugs [].However, after administration, free drugs are also trapped in the normal tissue because of the low selectivity for tumor tissue [].Nanomedicine is a rising field that possesses the main advantages of effectively targeted drug delivery to the tumor cells through enhanced permeation and retention (EPR ...

  • Energy barriers to anion transport in polyelectrolyte ...

    2020-5-15 · Membrane thickness increased significantly with the addition of bilayers to the PEMs while pore size and surface zeta potential were comparatively unaffected ().The similarity in pore size was particularly important for measurements of energy barriers to ion transport through the membranes, given the reported effect of steric hindrance on ion dehydration (i.e., greater need …Frontiers | Improved Alignment of PEDOT:PSS Induced by …Dimethylsulfone (DMSO2), a small organic molecule, was observed to induce the alignment of poly(3,4-ethylenedioxythiophene): poly(4-styrenesulfonate) (PEDOT:PSS) via in-situ crystallization in PEDOT:PSS mixture, which was …

  • Albumin-based drug delivery: harnessing nature to cure ...

    2016-2-27 · The effectiveness of a drug is dependent on accumulation at the site of action at therapeutic levels, however, challenges such as rapid renal clearance, degradation or non-specific accumulation requires drug delivery enabling technologies. Albumin is a natural transport protein with multiple ligand binding sites, cellular receptor engagement, and a long circulatory half-life …Frontiers | Molecular Modeling for Nanomaterial–Biology .. jection of nanoparticles (NP) into the bloodstream leads to the formation of a so-called "nano–bio" interface where dynamic interactions between nanoparticle surfaces and blood components take place. A common consequence is the formation of the protein corona, that is, a network of adsorbed proteins that can strongly alter the surface properties of the nanoparticle.

  • Isolation and chemical analysis of nanoparticles from ...

    Melzer B, Steinbrecher T, Seidel R, Kraft O, Schwaiger R& Speck T. 2010 The attachment strategy of English ivy: a complex mechanism acting on several hierarchical levels . J.Molecular dynamics simulations of ion transport through ...2010-4-28 · Extensive molecular dynamics simulations of the flow of aqueous NaCl and NaI solutions through carbon nanotubes are presented, evidencing the dependence of diverse transport features on the solute specificity, the nanotube geometry, and the various atomic models employed, including polarizability. The simulated properties are in agreement with published …

  • Albumin-based drug delivery: harnessing nature to cure ...

    2016-2-27 · The effectiveness of a drug is dependent on accumulation at the site of action at therapeutic levels, however, challenges such as rapid renal clearance, degradation or non-specific accumulation requires drug delivery enabling technologies. Albumin is a natural transport protein with multiple ligand binding sites, cellular receptor engagement, and a long circulatory half-life …(PDF) Albumin-based drug delivery: Harnessing, nature to ...Albumin-based drug delivery strategies. a Albumin fusion-based drugs, in light green (HSA) and in red (fusion peptide) (modified PDB 1e7e + 3IOL). b Albumin associating drugs; upper left binding ...

  • Ion-cut lithium niobate on insulator technology: Recent ...

    2021-2-4 · Lithium niobate (LiNbO 3 or LN) is a well-known multifunctional crystal that has been widely applied in various areas of photonics, electronics, and optoelectronics. In the past decade, "ion-cut" has become the key technique to produce wafer-size, high-quality, sub micrometer-thickness crystalline LiNbO 3 thin films, i.e., lithium-niobate-on-insulator (LNOI).Isolation and chemical analysis of nanoparticles from ...2020-1-1 · In this work, we focus on two different types of vesicles of zero spontaneous curvature. The vesicle of the first type is assumed to have a fixed total surface area A (= 4 π R 2) and its bending deformation obeys the Canham–Helfrich model .Therefore, the total system energy at the indentation depth Δ h is described by the Helfrich functional as,, E tot = 2 κ ∫ M 1 2 d A 1 + 2 …

  • Isolation and chemical analysis of nanoparticles from ...

    Melzer B, Steinbrecher T, Seidel R, Kraft O, Schwaiger R& Speck T. 2010 The attachment strategy of English ivy: a complex mechanism acting on several hierarchical levels . J.Carbon Dots: An Innovative Tool for Drug Delivery in Brain ...The pharmacological treatment of tumors of the central nervous system poses major challenges due to the presence of physical obstacles, i.e., the blood-brain barrier, impeding the delivery of anticancer drugs to the tumor site. Hence, the development ...

  • Rational design of mirror-like peptides with alanine ...

    2015-9-18 · Amino acids sequence distribution on helical wheel projections. By default the output of presented the amino acid residues as circles.Hydrophobic residues were coded X and blue background.Cationic residues were coded Y and red background.Dotted lines represented symmetrical axis on helical wheels.Left 13-amino acid in length was a perfectly amphipathic α …Albumin-based drug delivery: harnessing nature to cure …2015-11-13 · Biological properties of albumin. Albumin is the most abundant plasma protein in human blood (35–50 g/L human serum) with a molecular weight of 66.5 kDa [] is synthesised in the liver hepatocytes with ~ 10–15 g of albumin produced and released into the vascular space daily [10, 12].Circulation in the blood proceeds for an extended period of ~ 19 days [10, 13, 14].

  • Surface chemistry-mediated modulation of adsorbed …

    2021-1-1 · Controlling nanocarrier interactions with the immune system requires a thorough understanding of the surface properties that modulate protein adsorption in biological fluids, since the resulting protein corona redefines cellular interactions with nanocarrier surfaces ontiers | Molecular Modeling for Nanomaterial–Biology .. jection of nanoparticles (NP) into the bloodstream leads to the formation of a so-called "nano–bio" interface where dynamic interactions between nanoparticle surfaces and blood components take place. A common consequence is the formation of the protein corona, that is, a network of adsorbed proteins that can strongly alter the surface properties of the nanoparticle.

  • KIT

    S. Reißer, E. Strandberg, T. Steinbrecher, M. Elstner, A.S. Ulrich. Best of two worlds? How MD simulations of amphiphilic helical peptides in membranes can complement data from oriented solid-state NMR. J. Chem. Theory Comput. 14, 6002-6014 (2018)Imaging of the immune system – towards a subcellular and ...2020-3-1 · Introduction. The complexity of the immune system makes the imaging of various immune cells as a whole demanding but also worthwhile. Although non-optical methods, such as positron emission tomography (PET) and magnetic resonance imaging (MRI) exist (Willmann et al., 2008), their resolution is not at the single-cell level.Hence, this Review will be limited to …

  • Design and Application of Near-Infrared Nanomaterial ...

    1. Introduction. Currently, cancer treatment mainly relies on chemotherapeutic drugs [].However, after administration, free drugs are also trapped in the normal tissue because of the low selectivity for tumor tissue [].Nanomedicine is a rising field that possesses the main advantages of effectively targeted drug delivery to the tumor cells through enhanced permeation and retention (EPR ...Antibacterial Activity of T22, a Specific Peptidic Ligand ...1. Introduction. The peptide T22, also known as [Tyr5,12,Lys7]-polyphemusin II, is a 18-mer derivative of the horseshoe crab cationic antimicrobial peptide (AMP) polyphemusin I, in which three amino acid replacements enable it for a precise binding to the cell surface chemokine receptor CXCR4 [1,2].Since CXCR4 is an HIV co-receptor [], T22 was developed as an anti …

  • Nanoparticles Secreted from Ivy Rootlets for Surface ...

    2021-3-11 · Using atomic force microscopy, we observed ivy secretes nanoparticles through adhering disks of the ivy aerial rootlets which allow the plant to affix to a surface. We analyzed the organic composition of the secretions using high-performance liquid chromatography/mass spectrometry and were able to determine the formula of 19 compounds. This study suggests …The attachment strategy of English ivy: a complex ...2010-5-12 · English ivy (Hedera helix L.) is able to grow on vertical substrates such as trees, rocks and house plaster, thereby attaching so firmly to the surface that when removed by force typically whole pieces of the climbing substrate are torn off.The structural details of the attachment process are not yet entirely understood. We studied the attachment process of English ivy in …

  • Perspective on the Martini model

    Perspective on the Martini model S. J. Marrink and D. P. Tieleman, Chem. Soc. Rev., 2013, 42, 6801 DOI: 10.1039/C3CS60093A This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is …Frontiers | Improved Alignment of PEDOT:PSS Induced by …Dimethylsulfone (DMSO2), a small organic molecule, was observed to induce the alignment of poly(3,4-ethylenedioxythiophene): poly(4-styrenesulfonate) (PEDOT:PSS) via in-situ crystallization in PEDOT:PSS mixture, which was …

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